Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] waikawa succinic me (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS Nama 477600 -71-8

He mea tino nui a maatau takawaenga tofacitinib i roto i te mahi hanga tofacitinib, he rongoa rongonui e whakamahia ana ki te rongoa i etahi momo mate pukupuku.Ka whai waahi nui tenei takawaenga ki te hanga tofacitinib, ka whai waahi ki te whai hua me te kounga.Ma te (2R,3R)-2,3-bis [(4-methylbenzoyl)oxy] waikawa succinic me te (3R,4R)-N,4-dimethyl-1-(phenylmethyl)- Ko te huinga tika o te 3-piperidinamines, to tatou Ko te hua e whakarite ana i te whakahiato o te tofacitinib kounga teitei e tutuki ana, e eke ana ki nga paerewa ahumahi.

Ko te tauira irapoi me te taumaha o to tatou takawaenga tofacitinib e whakaatu ana i tona ma me tona kaha, ka waiho hei waahanga pono o te mahi hanga rongoa.Ma nga kai kua oti te ine, ka whakamanahia e tenei takawaenga te rite me te kaha o te hua whakamutunga, tofacitinib.Ka whai waahi ano nga taonga ngota i te tofacitinib ki te pumau me te oranga o te papa, me te whai hua me te pono mo te wa roa.